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Test Code MANN Alpha-Mannosidase, Leukocytes

Reporting Name

Alpha-Mannosidase, Leukocytes

Useful For

Diagnosis of alpha-mannosidosis

 

This test is not useful for establishing carrier status for alpha-mannosidosis.

Method Name

Fluorometric

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Whole Blood ACD


Ordering Guidance


If clinically suspicious of an oligosaccharidosis, screening tests are available. Order either OLIGU / Oligosaccharide Screen, Random, Urine or LSDS / Lysosomal Disorders Screen, Random, Urine which includes a combined analysis of ceramide trihexosides, mucopolysaccharides, oligosaccharides, sulfatides, and total and free sialic acid.



Shipping Instructions


For optimal isolation of leukocytes, it is recommended the specimen arrive refrigerated within 6 days of collection to be stabilized. Pre-analytical processing is performed Monday through Friday and Sunday. This test may be canceled if specimens are outside of stability when processing occurs. Collect and package specimens for arrival on days when processing is performed.



Specimen Required


Container/Tube:

Preferred: Yellow top (ACD solution B)

Acceptable: Yellow top (ACD solution A)

Specimen Volume: 6 mL

Collection Instructions: Send specimen in original tube. Do not aliquot.


Specimen Minimum Volume

5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Whole Blood ACD Refrigerated (preferred) 6 days YELLOW TOP/ACD
  Ambient  6 days YELLOW TOP/ACD

Reject Due To

Gross hemolysis Reject

Reference Values

≥0.54 nmol/min/mg protein

Day(s) Performed

Preanalytical processing: Monday through Friday, Sunday

Assay performed: Friday

CPT Code Information

82657

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MANN Alpha-Mannosidase, Leukocytes 24053-1

 

Result ID Test Result Name Result LOINC Value
35639 Alpha-Mannosidase, Leukocytes 24053-1
35640 Interpretation (MANN) 59462-2
35641 Reviewed By 18771-6

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 8 days