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Test Code MMAP Methylmalonic Acid, Quantitative, Plasma

Reporting Name

Methylmalonic Acid, QN, P

Useful For

Evaluating children with signs and symptoms of methylmalonic acidemia using plasma specimens

 

Evaluating individuals with signs and symptoms associated with a variety of causes of vitamin B12 (cobalamin) deficiency

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Plasma


Specimen Required


Collection Container/Tube:

Preferred: Green top (sodium heparin)

Acceptable: Lavender top (EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot plasma into a plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Refrigerated (preferred) 48 days
  Ambient  48 days
  Frozen  48 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

≤0.40 nmol/mL

Day(s) Performed

Monday through Friday

CPT Code Information

83921

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MMAP Methylmalonic Acid, QN, P 13964-2

 

Result ID Test Result Name Result LOINC Value
31927 Methylmalonic Acid, QN, P 13964-2

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

3 to 5 days