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Test Code NICOU Nicotine and Metabolites, Random, Urine

Reporting Name

Nicotine and Metabolites, U

Useful For

Monitoring tobacco use

 

Monitoring patients on nicotine-replacement therapy for concurrent use of tobacco products

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 3 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Specimen Minimum Volume

2 mL

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 28 days
  Frozen  365 days
  Ambient  28 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values

Non-tobacco user with no passive exposure:

Nicotine <5.0 ng/mL

 

Cotinine

<5.0 ng/mL

 

Anabasine

<2.0 ng/mL

 

Nornicotine

<2.0 ng/mL

Day(s) Performed

Monday through Sunday

CPT Code Information

80323

G0480 (if appropriate)

LOINC Code Information

Test ID Test Order Name Order LOINC Value
NICOU Nicotine and Metabolites, U 43125-4

 

Result ID Test Result Name Result LOINC Value
82510 Nicotine 3854-7
21321 Cotinine 10366-3
21324 Nornicotine 33917-6
21323 Anabasine 33915-0

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

Report Available

2 to 5 days