Test Code OPATM Opiate Confirmation, Meconium
Reporting Name
Opiate Confirmation, MUseful For
Detecting maternal prenatal opiate/opioid use up to 5 months before birth
Method Name
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Performing Laboratory
 Mayo Clinic Laboratories in Rochester
Specimen Type
MeconiumOrdering Guidance
For chain-of-custody testing, order OPTMX / Opiate Confirmation, Chain of Custody, Meconium.
Specimen Required
Supplies: Stool container, Small (Random), 4 oz (T288)
Container/Tube: Stool container
Specimen Volume: 1 g (approximately 1 teaspoon)
Collection Instructions: Collect entire random meconium specimen.
Specimen Minimum Volume
0.3 g (approximately 1/4 teaspoon)
Specimen Stability Information
| Specimen Type | Temperature | Time | 
|---|---|---|
| Meconium | Frozen (preferred) | 28 days | 
| Refrigerated | 28 days | |
| Ambient | 14 days | 
Reject Due To
| Grossly bloody | Reject; Pink OK | 
| Stool Diapers  | 
Reject | 
Special Instructions
Reference Values
Negative
Positives are reported with a quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) result.
Cutoff concentrations for LC-MS/MS testing:
Codeine: 20 ng/g
Hydrocodone: 20 ng/g
Hydromorphone: 20 ng/g
Morphine: 20 ng/g
Oxycodone: 20 ng/g
Oxymorphone: 20 ng/g
Day(s) Performed
Monday through Sunday
CPT Code Information
G0480
80361 (if appropriate for select payers)
80365 (if appropriate for select payers)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value | 
|---|---|---|
| OPATM | Opiate Confirmation, M | 69026-3 | 
| Result ID | Test Result Name | Result LOINC Value | 
|---|---|---|
| 31848 | Morphine | 69027-1 | 
| 31850 | Oxymorphone | 69028-9 | 
| 31849 | Hydromorphone | 68541-2 | 
| 31847 | Codeine | 68542-0 | 
| 31852 | Oxycodone | 68543-8 | 
| 31851 | Hydrocodone | 68544-6 | 
| 31868 | Interpretation | 8215-6 | 
| 31869 | Chain of Custody | 77202-0 |