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Test Code OPTU Orthostatic Protein, Timed Collection, Urine

Reporting Name

Orthostatic Protein, U

Useful For

Diagnosis of orthostatic proteinuria

 

As a second-order test for additional characterization of proteinuria of less than 3 grams/24 hours, particularly in children or adolescents

Profile Information

Test ID Reporting Name Available Separately Always Performed
DOPTU Daytime Orthostatic Protein, U No Yes
NOPTU Nighttime Orthostatic Protein, U No Yes

Method Name

Turbidimetry

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Ordering Guidance


This collection process requires 2 separate urine collections within a 24-hour period.

 

Collect specimen per instructions in Orthostatic Protein Measurement 24-Hour Urine: Collection Site Instructions (T546) in Special Instructions.



Necessary Information


This collection process requires 2 separate urine collections within a 24-hour period.

-Submit start and end times for collection and 16-hour volume (required).

-Submit start and end times for collection and 8-hour volume (required).



Specimen Required


Specimens should be collected before fluorescein is given or not collected until at least 24 hour later.

 

Supplies: 2 Sarstedt 5 mL Aliquot Tube (T914)

Daytime Collection

Container/Tube: Plastic, 5-mL tube

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a 16-hour (daytime) urine specimen.

2. No preservative.

3. Invert well before taking 4-mL aliquot.

4. Do not over fill aliquot tube 4 mL at most.

5. Collect specimen per instructions in Orthostatic Protein Measurement 24-Hour Urine: Collection Site Instructions (T546) in Special Instructions.

 

Nighttime (Supine) Collection

Container/Tube: Plastic, 5-mL tube

Specimen Volume: 4 mL

Collection Instructions:

1. Collect an 8-hour (nighttime) urine specimen.

2. No preservative.

3. Invert well before taking 4-mL aliquot at most.


Specimen Minimum Volume

1 mL from 16-hour (daytime) urine collection/1 mL from 8-hour (nighttime) urine collection

Specimen Stability Information

Specimen Type Temperature Time
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  24 hours

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Nighttime (supine) collection: <68 mg/8 hours

Reference values have not been established for patients <18 years of age.

 

Daytime collection: <197 mg/16 hours

Reference values have not been established for patients <18 years of age

Day(s) Performed

Monday through Sunday

CPT Code Information

84156 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
OPTU Orthostatic Protein, U 1755-8

 

Result ID Test Result Name Result LOINC Value
DPTU Total Protein, 16 HR, U 49002-9
NPTU Total Protein, 8 HR, U 50209-6
DUR7 Nighttime collection duration 13362-9
DUR4 Daytime collection duration 13362-9
DVOL Day volume 19153-6
VL Night volume 19153-6
NPRO Total Protein Conc, 8 HR, U 35663-4
DPRO Total Protein Conc, 16 HR, U 35663-4

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

Report Available

Same day/1 to 4 days