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Test Code PLPMA Prolactin, Pituitary Macroadenoma, Serum

Useful For

Quantifying prolactin in serum specimens where the high-dose hook effect is suspected (eg, presence of pituitary tumor with symptoms of prolactinoma, and lower than expected serum prolactin concentration)

Testing Algorithm

A pituitary adenoma should be identified by imaging studies prior to ordering this test.

Reporting Name

Prolactin, Pituitary Macroadenoma

Specimen Type

Serum


Ordering Guidance


For initial patient assessment; order PRL / Prolactin, Serum as the screening test.



Necessary Information


Patient's age and sex are required.



Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 2 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

1.75 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  90 days
  Ambient  24 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

Males

<18 years: not established

≥18 years: 4.0-15.2 ng/mL

 

Females:

<18 years: not established

≥18 years: 4.8-23.3 ng/mL 

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84146

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PLPMA Prolactin, Pituitary Macroadenoma 20568-2

 

Result ID Test Result Name Result LOINC Value
PRLR Prolactin, S 20568-2
CMT89 Comment 48767-8

Method Name

Electrochemiluminescent Immunoassay

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.