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Test Code TTAG Tissue Transglutaminase (tTG) Antibodies, IgA and IgG Profile, Serum


Specimen Required


Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Useful For

Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disease, positivity for HLA DQ2 and/or DQ8)

 

Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease

Profile Information

Test ID Reporting Name Available Separately Always Performed
TTLG Tissue Transglutaminase Ab, IgG, S Yes Yes
TTLA Tissue Transglutaminase Ab, IgA, S Yes Yes

Testing Algorithm

The following algorithms are available in Special Instructions:

-Celiac Disease Comprehensive Cascade

-Celiac Disease Diagnostic Testing Algorithm

-Celiac Disease Gluten-Free Cascade        

-Celiac Disease Routine Treatment Monitoring Algorithm

-Celiac Disease Serology Cascade

Method Name

Multiplex Flow Immunoassay

Reporting Name

Tissue Transglutaminase Ab, IgA/IgG

Specimen Type

Serum

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  240 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Reference Values

tTG Antibody, IgA

<15.0 U/mL (Negative)

 

tTG Antibody, IgG

<15.0 U/mL (Negative)

Performing Laboratory

MCHS- La Crosse Lab

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86364 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TTAG Tissue Transglutaminase Ab, IgA/IgG 35681-6

 

Result ID Test Result Name Result LOINC Value
TTLG Tissue Transglutaminase Ab, IgG, S 56537-4
TTLA Tissue Transglutaminase Ab, IgA, S 46128-5

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 3 days