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HelpTest Code TTLA Tissue Transglutaminase (tTG) Antibody, IgA, Serum
Specimen Required
Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Specimen Volume: 0.5 mL
Useful For
Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8)
Screening test for dermatitis herpetiformis, in conjunction with endomysial antibody test
Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease
Testing Algorithm
The following algorithms are available in Special Instructions:
-Celiac Disease Comprehensive Cascade
-Celiac Disease Diagnostic Testing Algorithm
-Celiac Disease Gluten-Free Cascade
-Celiac Disease Routine Treatment Monitoring Algorithm
-Celiac Disease Serology Cascade
Method Name
Multiplex Flow Immunoassay
Reporting Name
Tissue Transglutaminase Ab, IgA, SSpecimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Refrigerated (preferred) | 7 days |
| Frozen | 240 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | OK |
Reference Values
<15.0 U/mL (Negative)
Performing Laboratory
MCHS- La Crosse LabTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.CPT Code Information
86364
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TTLA | Tissue Transglutaminase Ab, IgA, S | 46128-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TTLA | Tissue Transglutaminase Ab, IgA, S | 46128-5 |
Day(s) Performed
Monday through Sunday